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Fast Kinetics

G-protein couple receptors are an important highly druggable gene family. Upon receptor activation, a wide range of second messengers are activated to illicit many different cellular responses. These second messengers include the mobilization of Ca2+, increase or reduction of intracellular cAMP, production of diacylglycerol and phospatidylinositols. These second messengers can be monitored kinetically using fluorescent reagents and biosensors.

 

GPCR Signaling Pathways
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Application Notes:

 

Visual Abstracts (.mp4):

BioTek’s Visual Abstracts are brief animated presentations describing the Augmented Microscopy workflow of a specific application.

Calcium Kinetics
Calcium Kinetics

Kinetic Characterization
Kinetic Characterization of Gs- and Gi-Dependent Regulation of cAMP

 

 

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Learn more about GPCR Second Messengers applications - search our Application Notes and technical documentation in Resources.

 

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