Recursos Técnicos - Resúmenes Visuales

Comet Assay: Single Cell Genotoxicity Measurement

Related Products: Lector Multi-Modal y de Captura de Imágenes Celulares Cytation 1, Lector Multi-Modal y de Captura de Imágenes Celulares Cytation 5, Microscopio Automatizado Lionheart FX

November 13, 2018

The comet assay quantifies genotoxicity in single cells. It uses gel electrophoresis to separate damaged DNA which are then visualized by DNA binding fluorescent probes. Image analysis determines intact DNA (comet head) and fractured DNA (comet tail). The more damage, the greater the proportion of DNA in the tail.

 


link